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GK diabetic rats subjected to controlled exercise regimens demonstrated that increased oxidative stress due to increased production of reactive oxygen species (ROS), lipid/protein peroxidation, and nitric oxide (NO) production resulted in alterations in glutathione (GSH)-dependent antioxidant defense metabolism which protects the pancreas from diabetes-induced pathological changes (Raza et al., 2016)

Hydration plays an important role in overall skin health

This balancing effect provides welcome side benefits for those managing combination skin challenges

It cannot be used directly for FDA new drug applications